Evaluation of four sampling devices for Burkholderia pseudomallei laboratory aerosol studies
نویسندگان
چکیده
منابع مشابه
Comparative Burkholderia pseudomallei natural history virulence studies using an aerosol murine model of infection
Melioidosis is an endemic disease caused by the bacterium Burkholderia pseudomallei. Concerns exist regarding B. pseudomallei use as a potential bio-threat agent causing persistent infections and typically manifesting as severe pneumonia capable of causing fatal bacteremia. Development of suitable therapeutics against melioidosis is complicated due to high degree of genetic and phenotypic varia...
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Burkholderia thailandensis is used in the laboratory as a surrogate of the more virulent B. pseudomallei. Since inhalation is believed to be a natural route of infection for B. pseudomallei, many animal studies with B. pseudomallei and B. thailandensis utilize the inhalation route of exposure. The aim of the present study was to quantify the recovery efficiency of culturable B. thailandensis fr...
متن کاملEvaluation of a Latex Agglutination Assay for the Identification of Burkholderia pseudomallei and Burkholderia mallei
Cases of melioidosis and glanders are rare in the United States, but the etiologic agents of each disease (Burkholderia pseudomallei and Burkholderia mallei, respectively) are classified as Tier 1 select agents because of concerns about their potential use as bioterrorism agents. A rapid, highly sensitive, and portable assay for clinical laboratories and field use is required. Our laboratory ha...
متن کاملFatal Burkholderia pseudomallei septicaemia.
Melioidosis, the infection caused by the saprophytic bacterium Burkholderia pseudomallei, is endemic in south-east Asia and northern Australia [1]. Sporadic cases have been reported from the Indian subcontinent and it is an emerging infection in India [2]. A low prevalence of antibodies against melioidosis among hospitalassociated groups in Colombo had been reported in 1976 [3], as well as a re...
متن کاملComparison of Ashdown's medium, Burkholderia cepacia medium, and Burkholderia pseudomallei selective agar for clinical isolation of Burkholderia pseudomallei.
Ashdown's medium, Burkholderia pseudomallei selective agar (BPSA), and a commercial Burkholderia cepacia medium were compared for their abilities to grow B. pseudomallei from 155 clinical specimens that proved positive for this organism. The sensitivity of each was equivalent; the selectivity of BPSA was lower than that of Ashdown's or B. cepacia medium.
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ژورنال
عنوان ژورنال: PLOS Neglected Tropical Diseases
سال: 2021
ISSN: 1935-2735
DOI: 10.1371/journal.pntd.0009001